During the 1960s, Dengue casualties were reduced significantly with the advent of vaccines and anti-biotic along with deadly viruses such as smallpox, poliomyelitis, and acute rheumatic fever. But Dengue is more than just a seasonal disease, as opposed to the others mentioned above. It is a killer spurned by poverty, social exclusion, health systems, environments, food security, water and sanitation. To win against it, proper education is very important. To truly win against the disease, public health vigilance in terms of modern structures will be needed. This will include disease monitoring, disease prevention, communication, and financial supports are all needed.